Orthopaedics, Muscle & Bone

Imaging of the Hand and Wrist

Surgical treatment for Carpal Tunnel Syndrome has existed for nearly a century without fundamental changes despite the associated complications (e.g., pain and weakness). Non-surgical interventions using manual therapies have attempted to treat CTS, yet their long-term efficacy is disputable due to a lack of scientific and clinical evidence.

Primary disease category:

Secondary disease category(ies):

Arthritis, Orthopaedics, Muscle & Bone

Imaging of the Hand and Wrist

Surgical treatment for Carpal Tunnel Syndrome has existed for nearly a century without fundamental changes despite the associated complications (e.g., pain and weakness). Non-surgical interventions using manual therapies have attempted to treat CTS, yet their long-term efficacy is disputable due to a lack of scientific and clinical evidence.

Primary disease category:

Orthopaedics, Muscle & Bone

Secondary disease category(ies):

Arthritis, Orthopaedics, Muscle & Bone

Cortical Sensorimotor Mechanisms of Carpal Tunnel Syndrome

Carpal Tunnel Syndrome (CTS) remains an elusive, unsolved medical problem. Current mainstream approaches address the problem at the site of symptoms, but this approach only partially accounts for the causes and effects of CTS. Growing evidence suggests that CTS impacts not only the nervous system at the hand, but also impacts the brain.

Primary disease category:

Brain, Spinal Cord & Nervous System

Secondary disease category(ies):

Brain, Spinal Cord & Nervous System, Healthy Volunteers, Orthopaedics, Muscle & Bone

A Multi-Center, Randomized, Pivotal Study Evaluating AMPLEX® Compared ToAutogenous Bone Graft in Subjects Indicated for Arthrodesis Surgery Involving the Hindfootor Ankle

The purpose of the study is to demonstrate that AMPLEX is non-inferior to autogenous bone graft (ABG) for bone fusion in a population indicated for single, double, or triple hindfoot arthrodesis (fusion) or ankle arthrodesis (fusion) surgery with supplemental graft material.

Primary disease category:

Orthopaedics, Muscle & Bone

Hip Fracture Evaluation with Alternatives of Total Hip Arthroplasty versus Hemi-Arthroplasty (HEALTH): A Multi-Centre Randomized Trial Comparing Total Hip Arthroplasty on Revision Surgery and Quality of Life in Patients with Displaced Femoral Neck F

In an elderly population undergoing treatment for displaced, femoral-neck fractures, whether a total or partial hip replacement may have similar or lower rates of revision surgery and higher functional outcome scores at 24 months is unknown. The primary objective is to determine the rates of revision surgery at 2 years in elderly subjects treated for displaced, femoral-neck fractures utilizing a total vs hemi replacement. The secondary objectives are to evaluate quality of life, function, and additional descriptors.

Primary disease category:

Orthopaedics, Muscle & Bone

A Multi-Center, Randomized, Controlled, Trial of Cerebrospinal Fluid Drainage in Acute Spinal Cord Injury

The purpose of this Phase IIB randomized control trial (RCT) is to evaluate the safety and efficacy of cerebrospinal fluid drainage (CSFD) and to provide a preliminary clinical efficacy evaluation of the combination of CSFD and elevation of MAP in patients with acute SCI.

Primary disease category:

Orthopaedics, Muscle & Bone