Diabetes mellitus has been shown to be a predictor of poor outcomes in hospitalized trauma patients. The current methods used for in-hospital blood sugar control have been proven to be outdated and ineffective when used alone. Studies have shown that the more modern methods used for at home blood sugar control are much more effective at maintaining normal blood sugar levels.
This study will be performed as a part of prospective observational American Association for the Surgery of Trauma (AAST) multi-institutional trial analyzing emergency department thoracotomies performed at trauma centers throughout the United States will be performed. After each EDT, all medical personnel involved in the resuscitation will complete a questionnaire. The primary endpoint will be occupational exposure during the thoracotomy. Secondary endpoints will include observance of universal precautions and proper reporting of occupational exposures using institutional protocols.
The purpose of this study is to develop a possible new treatment for influenza. This new treatment uses antibodies against this virus. Antibodies are natural proteins made by the body that attack influenza and other germs. We want to see if the plasma with higher levels of antibodies helps people with influenza improve more than plasma with lower levels or no antibodies. The plasma is given in addition to standard anti-influenza medications.
The primary objective is to demonstrate reversal of the anticoagulant effect of dabigatran. The secondary objectives are the assessment of bleeding, clinical outcomes, safety and the pharmacokinetics of dabigatran in the presence of idarucizumab.