Head & Neck Cancers

A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally Advanced Resected Head and Neck Cancer

This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with cetuximab in treating patients who have undergone surgery for locally advanced head and neck cancer.

Primary disease category:

Secondary disease category(ies):

Cancer, Head & Neck Cancers

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Trial of the Effects of Intravenous GC4419 on the Incidence and Duration of Severe Oral Mucositis (OM) in Patients Receiving Post-Operative or Definitive Therapy with Single-Agent

The main purpose of this study is to compare the effects of one of two different dose levels of an investigational drug called GC4419 when given with the standard radiation therapy and chemotherapy for the treatment of head and neck cancers. This study drug is not yet approved by the FDA. The study will be looking at the effect that the drug GC4419 will have on mucositis, which is a side effect of the chemotherapy and radiation therapy for the treatment of head and neck cancers.

Primary disease category:

Secondary disease category(ies):

Cancer, Head & Neck Cancers