Cancer

Leveraging social connection by including informal caregivers in an internet video conference-based compassion meditation intervention to reduce psychological distress in breast cancer survivors

The purpose of this study is to determine the effectiveness of two different wellness programs for breast cancer survivors and their family members. One program is called Cancer Health Education, and the other is called CBCT (Cognitively-Based Compassion Training). Both programs will be conducted online through Zoom (a video-based conference system) from your tablet or computer. The CBCT program will be delivered to survivors and a family member together, or just to the survivor

Primary disease category:

Cancer

Secondary disease category(ies):

Cancer, Breast Cancer

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IV squamous cell carcinoma of the head and neck who have undergone surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Primary disease category:

Cancer

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

This randomized phase II trial is studying radiation therapy with or without chemotherapy to see how well it works in treating patients with high-risk malignant salivary gland tumors that have been removed by surgery.

Primary disease category:

Cancer

Study of AM0010 With FOLFOX Compared to FOLFOX Alone Second-line Tx in Pts With Metastatic Pancreatic Cancer

This is an open-label, multi-center, randomized, Phase 3 study designed to compare the efficacy and safety of AM0010 in combination with FOLFOX versus FOLFOX alone in patients with metastatic adenocarcinoma of the pancreas who have progressed on one prior gemcitabine containing regimen.

Primary disease category:

Cancer

Study of REGN2810 and REGN1979 in Patients With Lymphoma or Acute Lymphoblastic Leukemia

The purpose of this study is to assess the safety and tolerability of REGN1979, an Anti-CD20 X Anti-CD3 Bispecific Monoclonal Antibody, and REGN2810, an Anti-Programmed Death-1 Monoclonal Antibody, in patients with B-cell malignancies.

Primary disease category:

Cancer

A Study Evaluating Venetoclax in Combination With Azacitidine Compared With Azacitidine Alone in Participants With Higher-Risk Myelodysplastic Syndromes (MDS) After Hypomethylating Agent-Failure

The purpose of this study is to evaluate the safety, pharmacokinetics and efficacy of Venetoclax as a single-agent and in combination with Azacitidine in subjects with high-risk myelodysplastic syndromes after hypomethylating agent-failure

Primary disease category:

Cancer

Phase 1 of EC1169 In Patients With Recurrent MCRPC

The purpose of this study is to determine the safety of EC1169 and the best dose to use in humans with recurrent Metastatic, Castration-Resistant Prostate Cancer (mCRPC). This study will also determine how EC1169 is distributed, broken down, passed and absorbed through your body and how quickly it is eliminated (leaves the body). All patients will receive EC1169.

Primary disease category:

Cancer

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