Cancer

Phase 1 of EC1169 In Patients With Recurrent MCRPC

The purpose of this study is to determine the safety of EC1169 and the best dose to use in humans with recurrent Metastatic, Castration-Resistant Prostate Cancer (mCRPC). This study will also determine how EC1169 is distributed, broken down, passed and absorbed through your body and how quickly it is eliminated (leaves the body). All patients will receive EC1169.

Primary disease category:

Cancer

A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 with Androgen Deprivation Therapy + Bicalutamide in Patients with Newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer

This study is for the treatment of metastatic hormone-sensitive prostate cancer.

Primary disease category:

Cancer

Secondary disease category(ies):

Cancer, Prostate Cancer

This study is for the treatment of stage III non-small cell lung cancer

Primary disease category:

Cancer

Secondary disease category(ies):

Cancer, Lung Cancer

Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients with Recurrent Stage IV Squamous Cell Lung Cancer

Primary disease category:

Cancer

Secondary disease category(ies):

Cancer, Lung Cancer

A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-small Cell Lung Cancer: Crizotinib Versus Placebo for Patients With Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein (ALCHEMIST) (E4512)

This study is for the treatment of non-small cell lung cancer.

Primary disease category:

Cancer

Secondary disease category(ies):

Cancer, Lung Cancer

Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR)Mutant Non-Small Cell Lung Cancer (NSCLC) (ALCHEMIST) (A081105)

This study is for the treatment of non-small cell lung cancer.

Primary disease category:

Cancer

Secondary disease category(ies):

Cancer, Lung Cancer

A Phase 1a/B Study Of The Folic Acid-Tubulysin Conjugate EC1456 In Patients With Advanced Solid Tumors

This study is for the treatment of advanced solid tumors.

Primary disease category:

Cancer

Secondary disease category(ies):

Cancer, Lung Cancer

Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) - A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers

This study is for the treatment of non-small cell lung cancer.

Primary disease category:

Cancer

Secondary disease category(ies):

Cancer, Lung Cancer

Study of Haploidentical Bone Marrow Transplant with Post-Transplant Cyclophosphamide and/or Bendamustine

This is a Phase I/II, single center study to evaluate the safety and efficacy of substituting day +4 cyclophosphamide with post-transplant bendamustine in myeloablative (MAC) or reduced intensity conditioning (RIC) haploidentical hematopoietic cell transplantation (HHCT) for advanced leukemia and lymphoma patients. This study will follow the standard-of-care bone marrow transplant (BMT), with the only exception being to gradually substitute post-transplant cyclophosphamide (on day +4 after BMT) with bendamustine.

Primary disease category:

Cancer

A PHASE III TRIAL OF ADJUVANT CHEMOTHERAPY AS PRIMARY TREATMENT FOR LOCALLY ADVANCED CERVICAL CANCER COMPARED TO CHEMORADIATION ALONE: THE OUTBACK TRIAL (ANZGOG 0902/GOG-0274/RTOG 1174)

The aim of the study is to test the potential benefit of the addition of adjuvant chemotherapy following completion of primary chemoradiation for patients with locally advanced cervical cancer.

Primary disease category:

Cancer

Phase 1 of EC1169 In Patients With Recurrent MCRPC

A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 with Androgen Deprivation Therapy + Bicalutamide in Patients with Newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer

This study is for the treatment of stage III non-small cell lung cancer

Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients with Recurrent Stage IV Squamous Cell Lung Cancer

A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-small Cell Lung Cancer: Crizotinib Versus Placebo for Patients With Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein (ALCHEMIST) (E4512)

Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR)Mutant Non-Small Cell Lung Cancer (NSCLC) (ALCHEMIST) (A081105)

A Phase 1a/B Study Of The Folic Acid-Tubulysin Conjugate EC1456 In Patients With Advanced Solid Tumors

Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) - A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers

Study of Haploidentical Bone Marrow Transplant with Post-Transplant Cyclophosphamide and/or Bendamustine

A PHASE III TRIAL OF ADJUVANT CHEMOTHERAPY AS PRIMARY TREATMENT FOR LOCALLY ADVANCED CERVICAL CANCER COMPARED TO CHEMORADIATION ALONE: THE OUTBACK TRIAL (ANZGOG 0902/GOG-0274/RTOG 1174)

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