Understanding the Role of Mitochondria in Type 2 Diabetes

People who are obese or who have type 2 diabetes are insulin resistant. Insulin resistance is when the body does not use insulin correctly, and more insulin is needed to keep blood sugar levels normal. In this study we are trying to better understand the causes of insulin resistance.  People with insulin resistance have mitochondria that do not work well in muscle. Mitochondria are tiny parts of cells responsible for making energy, and we will be looking at these to see how they are involved in insulin resistance.

Study phase: N/A

Basic eligibility criteria:
Please contact the study coordinator for additional eligibility information.

  • Age: 21-55
  • Male or Female
  • With or without Type 2 Diabetes
  • For females: Not pregnant or breast feeding

Contact study coordinator for additional eligibility criteria

Primary disease category: Diabetes & Endocrine System

Secondary disease categories: Healthy Volunteers

Sponsor: American Diabetes Association

Protocol number: 1901254125

Projected enrollment dates: February 2019 to December 2021

Official study title: Unraveling the role of mitochondrial DNA methylation in type 2 diabetes