Linking Epidermal Barrier Function with Anti-Oxidant Defense Mechanisms in Atopic Dermatitis

The purpose of this study is to perform skin barrier measurements, and skin and serum histochemical studies in order to understand the correlation between oxidative stress, inflammatory markers, and skin barrier function in atopic dermatitis (eczema). Skin biopsy and blood specimens will be collected from patients with atopic dermatitis (eczema) for this study.

Basic eligibility criteria:
Please contact the study coordinator for additional eligibility information.

Inclusion criteria:
• Male and female, from 18 to 99 years of age.
• Adult subjects must be able to comprehend and read the English language.
• Subjects diagnosed with atopic dermatitis (eczema) or have healthy skin defined as without clinical evidence or diagnosis of inflammatory skin conditions.
• Subjects with atopic dermatitis (eczema) must have at least one active skin lesion.

Primary disease category: Dermatology

This study is enrolling healthy volunteers.

Projected enrollment dates: May 2017 to May 2019

Official study title: Linking Epidermal Barrier Function with Anti-Oxidant Defense Mechanisms in Atopic Dermatitis