This study will look at how particular proteins are involved in asthma. Specifically, the study will examine specific proteins called surfactant protein A and D (SP-A, SP-D, which help with surface tension) and look at the way the natural molecules hyaluronan (HA) and Snitrosoglutathione reductase (GSNOR) affect inflammatory and immunologic responses in allergic asthma. It is hoped that the information learned from this study can help researchers obtain a better understanding of the roles of SP-A, SP-D, GSNOR and HA and their effect on airway remodeling (permanent destruction of the airway) in asthma
Basic eligibility criteria:
Please contact the study coordinator for additional eligibility information.
Adults with asthma.
Primary disease category: Asthma & Lung
This study is enrolling healthy volunteers.
Protocol number: P01-HL108793-01A1
Projected enrollment dates: March 2015 to December 2017
Official study title: Hyaluronan