Epigenetics and the Origin of Muscle Insulin Resistance in Humans

Insulin is the hormone, produced normally by the body, which causes blood sugar to return to normal after eating. Insulin resistance is a state when the body is not using insulin correctly, and more insulin is needed to keep the sugar level normal. Insulin resistance can lead to Type 2 Diabetes. Type 2 diabetes is a disease in which blood sugar levels are too high. Our studies of DNA methylation may help to find out why some people develop Type 2 Diabetes. By studying this, we hope to better understand the causes of insulin resistance.

Basic eligibility criteria:
Please contact the study coordinator for additional eligibility information.

Male and Females ages 21 - 55

Primary disease category: Diabetes & Endocrine System

This study is enrolling healthy volunteers.

Sponsor: NIH/NIDDK

Projected enrollment dates: January 2017 to December 2018

Official study title: Epigenetics and the Origin of Muscle Insulin Resistance in Humans Aims 1-3