Brain, Spinal Cord & Nervous System

CASA Pilot Clinical Trial

This research proposes to evaluate the effectiveness of a novel device designed for the non-surgical treatment of carpal tunnel syndrome. The device applies a small cyclic force to the wrist. The cycles include a small time period in which force is applied, followed by a brief period of no force. The device is intended to be worn during hours of sleep. Treatment efficacy will be evaluated based on comparisons to patient reported outcomes for a standard of care treatment.

Primary disease category:

Orthopaedics, Muscle & Bone

Secondary disease category(ies):

Brain, Spinal Cord & Nervous System, Parkinson's Disease, Neuromuscular Disorders & Other Movement Disorders, Stroke, Aneurysms & Vascular Lesions

The role of gut microbiome in epilepsy

The propose of this pilot study is to test the hypothesis that children with epilepsy have changes in gut microbiome as compared to their siblings and controls.

Our specific aims are:

1. To compare the taxonomy of gut microbiome in patients with new onset epilepsy versus siblings and controls.

2. To compare the taxonomy of gut microbiome in patients with new onset epilepsy versus chronic and refractory epilepsy.

Primary disease category:

Children, Infants & Newborns

Secondary disease category(ies):

Brain, Spinal Cord & Nervous System, Epilepsy & Seizures, Children, Infants & Newborns, Healthy Volunteers